Version 5.4
Homo sapiens Protein: FSBP
Summary
InnateDB Protein IDBP-476413.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FSBP
Protein Name RAD54 homolog B (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000420405
InnateDB Gene IDBG-706379 (FSBP)
Protein Structure
UniProt Annotation
Function Transcriptional repressor that down-regulates the expression of the fibrinogen gamma chain. Represses transcription of GSK3B gene promoter via its interaction with APBA1. {ECO:0000269PubMed:20531236}.
Subcellular Localization Nucleus {ECO:0000269PubMed:20531236}.
Disease Associations
Tissue Specificity Expressed in multiple tissues including brain. {ECO:0000269PubMed:20531236}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0015616 DNA translocase activity
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006974 cellular response to DNA damage stimulus
GO:0010212 response to ionizing radiation
GO:0042493 response to drug
GO:0045449 regulation of transcription
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR029071 Ubiquitin-related domain
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O95073
PhosphoSite PhosphoSite-O95073
TrEMBL
UniProt Splice Variant
Entrez Gene 100861412
UniGene
RefSeq NP_001243070
HUGO HGNC:43653
OMIM
CCDS CCDS59106
HPRD
IMGT
EMBL AC023632 AF007866 AF487652 BC033710
GenPept AAD09313 AAH33710 AAL96666

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca