Version 5.4
Homo sapiens Protein: CCNH
Summary
InnateDB Protein IDBP-476473.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CCNH
Protein Name cyclin H
Synonyms CAK; CycH; p34; p37;
Species Homo sapiens
Ensembl Protein ENSP00000426075
InnateDB Gene IDBG-32948 (CCNH)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 55 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 55 [view]
Protein-Protein 54 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
GO:0019901 protein kinase binding
Biological Process
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0051726 regulation of cell cycle
Cellular Component
GO:0016591 DNA-directed RNA polymerase II, holoenzyme
GO:0070985 TFIIK complex
Protein Structure and Domains
PDB ID
InterPro IPR006671 Cyclin, N-terminal
IPR013763 Cyclin-like
IPR023598 Cyclin C
IPR027081 CyclinH/Ccl1
PFAM PF00134
PRINTS
PIRSF PIRSF028758
SMART SM00385
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D6RHI7
UniProt Splice Variant
Entrez Gene 902
UniGene Hs.677441
RefSeq NP_001186118
HUGO HGNC:1594
OMIM 601953
CCDS
HPRD 09059
IMGT
EMBL AC018754
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca