InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: B4GALT4

Summary

InnateDB Protein

IDBP-476927.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

B4GALT4

Protein Name

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4

Synonyms

B4Gal-T4; beta4Gal-T4;

Species

Homo sapiens

Ensembl Protein

ENSP00000420161

InnateDB Gene

IDBG-51106 (B4GALT4)

Protein Structure

UniProt Annotation

Function

Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. {ECO:0000269PubMed:9792633}.

Subcellular Localization

Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Trans cisternae of Golgi stack.

Disease Associations

Tissue Specificity

High expression in heart, placenta, kidney and pancreas; lower in brain, colon, lung, muscle, ovary, testis and uterus.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003945	N-acetyllactosamine synthase activity
GO:0008378	galactosyltransferase activity
GO:0016757	transferase activity, transferring glycosyl groups
GO:0046872	metal ion binding

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0006643	membrane lipid metabolic process
GO:0018146	keratan sulfate biosynthetic process
GO:0018279	protein N-linked glycosylation via asparagine
GO:0030203	glycosaminoglycan metabolic process
GO:0042339	keratan sulfate metabolic process
GO:0043687	post-translational protein modification
GO:0044267	cellular protein metabolic process
GO:0044281	small molecule metabolic process