InnateDB Protein
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IDBP-477043.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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HNRNPAB
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Protein Name
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heterogeneous nuclear ribonucleoprotein A/B
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Synonyms
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ABBP1; HNRPAB;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000427465
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InnateDB Gene
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IDBG-60841 (HNRNPAB)
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Protein Structure
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Function |
Binds single-stranded RNA. Has a high affinity for G- rich and U-rich regions of hnRNA. Also binds to APOB mRNA transcripts around the RNA editing site.
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Subcellular Localization |
Nucleus {ECO:0000269PubMed:17289661}. Cytoplasm {ECO:0000269PubMed:17289661}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
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Disease Associations |
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Tissue Specificity |
Ubiquitous.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 73 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated |
Total |
73
[view]
|
Protein-Protein |
73
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
6 [view]
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Molecular Function |
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Biological Process |
GO:0001837
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epithelial to mesenchymal transition
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GO:0045893
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positive regulation of transcription, DNA-templated
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Cellular Component |
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PDB ID |
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InterPro |
IPR000504
RNA recognition motif domain
IPR012956
CARG-binding factor, N-terminal
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PFAM |
PF00076
PF08143
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PRINTS |
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PIRSF |
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SMART |
SM00360
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TIGRFAMs |
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Modification |
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SwissProt |
Q99729
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PhosphoSite |
PhosphoSite-Q99729
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
3182
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UniGene |
Hs.591731
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RefSeq |
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HUGO |
HGNC:5034
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OMIM |
602688
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CCDS |
CCDS34310
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HPRD |
04067
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IMGT |
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EMBL |
AK054600
AK097657
BC001616
BC002625
BC004561
BC009359
BC036708
CH471165
M65028
U76713
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GenPept |
AAA36575
AAC50956
AAH01616
AAH02625
AAH04561
AAH09359
AAH36708
BAC05134
BAG51397
EAW53843
EAW53844
EAW53845
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