Version 5.4
Homo sapiens Protein: ST6GALNAC5
Summary
InnateDB Protein IDBP-477130.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ST6GALNAC5
Protein Name ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000417583
InnateDB Gene IDBG-99791 (ST6GALNAC5)
Protein Structure
UniProt Annotation
Function Involved in the biosynthesis of ganglioside GD1a from GM1b. It exhibits higher activity with glycolipids than with glycoproteins (By similarity). {ECO:0000250}.
Subcellular Localization Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity
GO:0008373 sialyltransferase activity
Biological Process
GO:0006486 protein glycosylation
GO:0006688 glycosphingolipid biosynthetic process
GO:0009312 oligosaccharide biosynthetic process
GO:0097503 sialylation
Cellular Component
GO:0030173 integral component of Golgi membrane
Protein Structure and Domains
PDB ID
InterPro IPR001675 Glycosyl transferase, family 29
IPR012163 Sialyltransferase
PFAM PF00777
PRINTS
PIRSF PIRSF005557
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BVH7
PhosphoSite PhosphoSite-Q9BVH7
TrEMBL V5N4G2
UniProt Splice Variant
Entrez Gene 81849
UniGene Hs.732053
RefSeq NP_112227
HUGO HGNC:19342
OMIM 610134
CCDS CCDS673
HPRD 15342
IMGT
EMBL AC099060 AJ507292 AK056241 AK295019 AL035409 BC001201 CH471059 KF548000
GenPept AAH01201 AHA82580 BAB71127 BAG58078 CAD45372 CAM28274 EAX06386

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca