Version 5.4
Homo sapiens Protein: PCSK1
Summary
InnateDB Protein IDBP-477488.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PCSK1
Protein Name proprotein convertase subtilisin/kexin type 1
Synonyms BMIQ12; NEC1; PC1; PC3; SPC3;
Species Homo sapiens
Ensembl Protein ENSP00000427294
InnateDB Gene IDBG-34238 (PCSK1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000209 Peptidase S8/S53 domain
IPR009020 Proteinase inhibitor, propeptide
PFAM PF00082
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D6RJA3
UniProt Splice Variant
Entrez Gene 5122
UniGene Hs.78977
RefSeq
HUGO HGNC:8743
OMIM 162150
CCDS
HPRD 01201
IMGT
EMBL AC008951 AC108107
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca