InnateDB Protein
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IDBP-477831.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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IRX4
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Protein Name
|
iroquois homeobox 4
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000423161
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InnateDB Gene
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IDBG-11333 (IRX4)
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Protein Structure
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|
Function |
Likely to be an important mediator of ventricular differentiation during cardiac development.
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Subcellular Localization |
Nucleus {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Predominantly expressed in cardiac ventricles.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
2
[view]
|
Protein-Protein |
2
[view]
|
Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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|
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Molecular Function |
Accession |
GO Term |
GO:0003677
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DNA binding
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GO:0003700
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sequence-specific DNA binding transcription factor activity
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GO:0043565
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sequence-specific DNA binding
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Biological Process |
GO:0006355
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regulation of transcription, DNA-templated
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Cellular Component |
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PDB ID |
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InterPro |
IPR001356
Homeobox domain
IPR003893
Iroquois-class homeodomain protein
IPR009057
Homeodomain-like
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PFAM |
PF00046
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PRINTS |
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PIRSF |
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SMART |
SM00389
SM00548
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TIGRFAMs |
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Modification |
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SwissProt |
P78413
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PhosphoSite |
PhosphoSite-P78413
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
50805
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UniGene |
|
RefSeq |
NP_001265563
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HUGO |
HGNC:6129
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OMIM |
606199
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CCDS |
CCDS3867
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HPRD |
09369
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IMGT |
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EMBL |
AB690778
AB690779
AB690780
AB690781
AF124733
AY335941
BC110912
BC136505
BC136506
CH471102
U90306
|
GenPept |
AAB50004
AAF23887
AAI10913
AAI36506
AAI36507
AAQ16547
BAL44219
BAL44220
BAL44221
BAL44222
EAX08138
EAX08139
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