Version 5.4
Homo sapiens Protein: TMEM192
Summary
InnateDB Protein IDBP-477856.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMEM192
Protein Name transmembrane protein 192
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000425335
InnateDB Gene IDBG-43512 (TMEM192)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Lysosome membrane; Multi-pass membrane protein. Late endosome.
Disease Associations
Tissue Specificity Strongly expressed in kidney, liver, lung and pancreas. {ECO:0000269PubMed:20370317}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0042803 protein homodimerization activity
Biological Process
Cellular Component
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005770 late endosome
GO:0016021 integral component of membrane
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IY95
PhosphoSite PhosphoSite-Q8IY95
TrEMBL D6RAZ6
UniProt Splice Variant
Entrez Gene 201931
UniGene Hs.729692
RefSeq
HUGO HGNC:26775
OMIM
CCDS
HPRD 08787
IMGT
EMBL AC055120 AC108465 AK095801 BC036301 BX538029 CH471056
GenPept AAH36301 BAC04628 CAD97974 EAX04826

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca