InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GSTA2

Summary

InnateDB Protein

IDBP-478102.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GSTA2

Protein Name

glutathione S-transferase alpha 2

Synonyms

GST2; GSTA2-2; GTA2; GTH2;

Species

Homo sapiens

Ensembl Protein

ENSP00000420168

InnateDB Gene

IDBG-408581 (GSTA2)

Protein Structure

UniProt Annotation

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Liver.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004364	glutathione transferase activity
GO:0005515	protein binding

Biological Process

GO:0006749	glutathione metabolic process
GO:0006805	xenobiotic metabolic process
GO:0030855	epithelial cell differentiation
GO:0044281	small molecule metabolic process
GO:1901687	glutathione derivative biosynthetic process

Cellular Component

GO:0005829

cytosol

Protein Structure and Domains

PDB ID

InterPro

IPR003080 Glutathione S-transferase, alpha class
IPR004045 Glutathione S-transferase, N-terminal
IPR004046 Glutathione S-transferase, C-terminal
IPR010987 Glutathione S-transferase, C-terminal-like
IPR012336 Thioredoxin-like fold

PFAM