Version 5.4
Homo sapiens Protein: CENPE
Summary
InnateDB Protein IDBP-478124.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CENPE
Protein Name centromere protein E, 312kDa
Synonyms CENP-E; KIF10; PPP1R61;
Species Homo sapiens
Ensembl Protein ENSP00000426023
InnateDB Gene IDBG-32488 (CENPE)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 28 [view]
Protein-Protein 24 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement
GO:0008152 metabolic process
Cellular Component
GO:0005871 kinesin complex
GO:0005874 microtubule
Protein Structure and Domains
PDB ID
InterPro IPR001752 Kinesin, motor domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00225
PRINTS PR00380
PIRSF
SMART SM00129
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D6RHK2
UniProt Splice Variant
Entrez Gene 1062
UniGene Hs.75573
RefSeq
HUGO HGNC:1856
OMIM 117143
CCDS
HPRD 00316
IMGT
EMBL AC079919
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca