Version 5.4
Homo sapiens Protein: NKX6-3
Summary
InnateDB Protein IDBP-478185.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NKX6-3
Protein Name NK6 homeobox 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000429553
InnateDB Gene IDBG-19042 (NKX6-3)
Protein Structure
UniProt Annotation
Function Putative transcription factor, which may be involved in patterning of central nervous system and pancreas. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00108}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0000976 transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
Biological Process
GO:0001709 cell fate determination
GO:0002067 glandular epithelial cell differentiation
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0030857 negative regulation of epithelial cell differentiation
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR009057 Homeodomain-like
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A6NJ46
PhosphoSite PhosphoSite-A6NJ46
TrEMBL
UniProt Splice Variant
Entrez Gene 157848
UniGene Hs.647132
RefSeq NP_689781
HUGO HGNC:26328
OMIM 610772
CCDS CCDS6118
HPRD 08053
IMGT
EMBL AC113133 AK057898 CH471080
GenPept BAB71610 EAW63251 EAW63252

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca