Version 5.4
Homo sapiens Protein: NEDD4
Summary
InnateDB Protein IDBP-478235.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NEDD4
Protein Name neural precursor cell expressed, developmentally down-regulated 4
Synonyms NEDD4-1; RPF1;
Species Homo sapiens
Ensembl Protein ENSP00000422455
InnateDB Gene IDBG-13236 (NEDD4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 333 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.
Experimentally validated
Total 333 [view]
Protein-Protein 333 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 29 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000569 HECT
IPR001202 WW domain
PFAM PF00632
PF00397
PRINTS
PIRSF
SMART SM00119
SM00456
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 4734
UniGene Hs.611783
RefSeq NP_001271269
HUGO HGNC:7727
OMIM 602278
CCDS
HPRD 03786
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca