InnateDB Protein
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IDBP-478339.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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RAB11FIP1
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Protein Name
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RAB11 family interacting protein 1 (class I)
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000430680
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InnateDB Gene
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IDBG-17106 (RAB11FIP1)
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Protein Structure
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Function |
A Rab11 effector protein involved in the endosomal recycling process. Also involved in controlling membrane trafficking along the phagocytic pathway and in phagocytosis. {ECO:0000269PubMed:11786538, ECO:0000269PubMed:15181150, ECO:0000269PubMed:15355514, ECO:0000269PubMed:16920206}.
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Subcellular Localization |
Recycling endosome {ECO:0000269PubMed:11786538, ECO:0000269PubMed:15181150, ECO:0000269PubMed:15280022, ECO:0000269PubMed:15355514, ECO:0000269PubMed:16920206}. Note=Rab11A rather than Rab4A mediates localization in the endocytic recycling compartment (ERC).Isoform 2: Cytoplasmic vesicle, phagosome membrane. Note=Membrane-bound (isoform 2). Colocalizes with Rab11A at phagosomes (isoform 2).
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Disease Associations |
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Tissue Specificity |
Isoform 2 is expressed in brain, heart, testis, lung, spleen, ovary and small intestine. {ECO:0000269PubMed:11786538}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
14
[view]
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Protein-Protein |
14
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q6WKZ4
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PhosphoSite |
PhosphoSite-Q6WKZ4
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
80223
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UniGene |
Hs.722480
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RefSeq |
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HUGO |
HGNC:30265
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OMIM |
608737
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CCDS |
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HPRD |
09787
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IMGT |
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EMBL |
AC130304
AF368294
AK026275
AK122583
AK291781
AY280966
AY280968
AY280970
BC077720
DQ236342
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GenPept |
AAH77720
AAM09571
AAQ18784
AAQ18786
AAQ18788
ABB43161
BAB15424
BAC56924
BAF84470
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