Version 5.4
Homo sapiens Protein: SQSTM1
Summary
InnateDB Protein IDBP-478633.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SQSTM1
Protein Name sequestosome 1
Synonyms A170; OSIL; p60; p62; p62B; PDB3; ZIP3;
Species Homo sapiens
Ensembl Protein ENSP00000425957
InnateDB Gene IDBG-61811 (SQSTM1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 502 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
Experimentally validated
Total 502 [view]
Protein-Protein 498 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 31 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0045087 innate immune response (InnateDB)
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000270 Phox/Bem1p
IPR000433 Zinc finger, ZZ-type
PFAM PF00564
PF00569
PRINTS
PIRSF
SMART SM00666
SM00291
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E3W990
UniProt Splice Variant
Entrez Gene 8878
UniGene Hs.724025
RefSeq
HUGO HGNC:11280
OMIM 601530
CCDS
HPRD 03319
IMGT
EMBL AC008393
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca