InnateDB Protein
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IDBP-478959.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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C3orf58
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Protein Name
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chromosome 3 open reading frame 58
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000417382
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InnateDB Gene
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IDBG-59948 (C3orf58)
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Protein Structure
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Function |
May play a role in cardiomyocyte proliferation through paracrine signaling and activation of the PPI3K-AKT-CDK7 signaling cascade. {ECO:0000269PubMed:23784961}.
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Subcellular Localization |
Cytoplasmic vesicle, COPI-coated vesicle. Golgi apparatus. Secreted.
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Disease Associations |
Note=Genetic variations in C3orf58 may be associated with susceptibility to autism.
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
GO:0014066
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regulation of phosphatidylinositol 3-kinase signaling
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GO:0060038
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cardiac muscle cell proliferation
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8NDZ4
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PhosphoSite |
PhosphoSite-Q8NDZ4
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TrEMBL |
E7ET39
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UniProt Splice Variant |
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Entrez Gene |
205428
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UniGene |
Hs.707239
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RefSeq |
NP_001127942
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HUGO |
HGNC:28490
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OMIM |
612200
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CCDS |
CCDS46929
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HPRD |
14559
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IMGT |
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EMBL |
AC117379
AC117387
AK294020
AK315082
BC037293
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GenPept |
AAH37293
BAG37549
BAH11649
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