InnateDB Protein
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IDBP-47901.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TRMT10C
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Protein Name
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RNA (guanine-9-) methyltransferase domain containing 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000312356
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InnateDB Gene
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IDBG-47899 (TRMT10C)
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Protein Structure
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Function |
Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. {ECO:0000269PubMed:18984158, ECO:0000269PubMed:21593607}.
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Subcellular Localization |
Mitochondrion matrix, mitochondrion nucleoid {ECO:0000269PubMed:18984158, ECO:0000269PubMed:23473034}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
14
[view]
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Protein-Protein |
14
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR016009
tRNA methyltransferase TRMD/TRM10-type domain
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PFAM |
PF01746
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q7L0Y3
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PhosphoSite |
PhosphoSite-Q7L0Y3
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TrEMBL |
C9JVB6
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UniProt Splice Variant |
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Entrez Gene |
54931
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UniGene |
Hs.740864
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RefSeq |
NP_060289
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HUGO |
HGNC:26022
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OMIM |
615423
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CCDS |
CCDS43122
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HPRD |
15240
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IMGT |
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EMBL |
AC073861
AF155111
AF226052
AK000439
AY561707
BC035967
CH471052
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GenPept |
AAD42877
AAF86952
AAH35967
AAS66980
BAA91166
EAW79795
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