Version 5.4
Homo sapiens Protein: SNCA
Summary
InnateDB Protein IDBP-479130.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNCA
Protein Name synuclein, alpha (non A4 component of amyloid precursor)
Synonyms NACP; PARK1; PARK4; PD1;
Species Homo sapiens
Ensembl Protein ENSP00000426034
InnateDB Gene IDBG-30077 (SNCA)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 384 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 384 [view]
Protein-Protein 380 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 4 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0014059 regulation of dopamine secretion
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001058 Synuclein
IPR002460 Alpha-synuclein
PFAM PF01387
PRINTS PR01211
PR01212
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q4W5L2
UniProt Splice Variant
Entrez Gene 6622
UniGene Hs.604559
RefSeq
HUGO HGNC:11138
OMIM 163890
CCDS
HPRD 01227
IMGT
EMBL AC093759 AC097478 AC108208 HQ830267 HQ830268 HQ830269
GenPept AAY40956 AEG20815 AEG20816 AEG20817

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca