InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: EIF3E

Summary

InnateDB Protein

IDBP-479291.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EIF3E

Protein Name

eukaryotic translation initiation factor 3, subunit E

Synonyms

eIF3-p46; EIF3-P48; EIF3S6; INT6;

Species

Homo sapiens

Ensembl Protein

ENSP00000428796

InnateDB Gene

IDBG-32393 (EIF3E)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 145 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	145 [view]
Protein-Protein	142 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003743	translation initiation factor activity
GO:0005515	protein binding

Biological Process

GO:0001731	formation of translation preinitiation complex
GO:0006446	regulation of translational initiation

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005852	eukaryotic translation initiation factor 3 complex
GO:0016282	eukaryotic 43S preinitiation complex
GO:0016605	PML body
GO:0033290	eukaryotic 48S preinitiation complex

Protein Structure and Domains

PDB ID

InterPro

IPR000717 Proteasome component (PCI) domain
IPR016650 Eukaryotic translation initiation factor 3 subunit E
IPR019010 Eukaryotic translation initiation factor 3 subunit E, N-terminal

PFAM

PF01399
PF09440

PRINTS

PIRSF

PIRSF016255

SMART

SM00088

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt