InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ACY1

Summary

InnateDB Protein

IDBP-479713.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ACY1

Protein Name

aminoacylase 1

Synonyms

ACY-1; ACY1D; HEL-S-5;

Species

Homo sapiens

Ensembl Protein

ENSP00000417056

InnateDB Gene

IDBG-409436 (ACY1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.

Experimentally validated
Total	12 [view]
Protein-Protein	11 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004046	aminoacylase activity
GO:0008237	metallopeptidase activity
GO:0016787	hydrolase activity
GO:0046872	metal ion binding

Biological Process

GO:0006508	proteolysis
GO:0006520	cellular amino acid metabolic process
GO:0008152	metabolic process

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR002933 Peptidase M20
IPR010159 N-acyl-L-amino-acid amidohydrolase
IPR011650 Peptidase M20, dimerisation domain

PFAM

PF01546
PF07687

PRINTS

PIRSF

PIRSF036696

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q03154

PhosphoSite

PhosphoSite-Q03154

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Hs.334707

RefSeq

NP_001185827

HUGO

HGNC:177

OMIM

104620

CCDS

CCDS56263

HPRD

00092

IMGT

EMBL

AC115284 BC000545 BC003023 BC014112 D14524 D16307 L07548

GenPept

AAA02852 AAH00545 AAH03023 AAH14112 BAA03397 BAA03814