InnateDB Protein
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IDBP-479867.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ABTB1
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Protein Name
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ankyrin repeat and BTB (POZ) domain containing 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000417366
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InnateDB Gene
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IDBG-54981 (ABTB1)
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Protein Structure
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Function |
May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes. {ECO:0000269PubMed:10891360, ECO:0000269PubMed:11494141}.
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Subcellular Localization |
Cytoplasm {ECO:0000269PubMed:11494141}.
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Disease Associations |
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Tissue Specificity |
Ubiquitously expressed in all fetal tissues examined including heart, brain, liver, and kidney. Also expressed at lower levels in both adult heart and hypertrophic heart. {ECO:0000269PubMed:10891360}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated |
Total |
7
[view]
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Protein-Protein |
7
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
3 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000210
BTB/POZ-like
IPR011333
BTB/POZ fold
IPR013069
BTB/POZ
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PFAM |
PF00651
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PRINTS |
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PIRSF |
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SMART |
SM00225
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TIGRFAMs |
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Modification |
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SwissProt |
Q969K4
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PhosphoSite |
PhosphoSite-Q969K4
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
80325
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UniGene |
Hs.107812
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RefSeq |
XP_006713835
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HUGO |
HGNC:18275
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OMIM |
608308
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CCDS |
CCDS46901
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HPRD |
10513
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IMGT |
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EMBL |
AB053324
AB053325
AB053326
AF297986
AF447886
AK130594
BC011858
CH471052
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GenPept |
AAH11858
AAK57478
AAQ04661
BAB55648
BAB55649
BAB55650
BAC85392
EAW79333
EAW79334
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