Version 5.4
Homo sapiens Protein: FAM170A
Summary
InnateDB Protein IDBP-480089.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAM170A
Protein Name family with sequence similarity 170, member A
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000422684
InnateDB Gene IDBG-38533 (FAM170A)
Protein Structure
UniProt Annotation
Function Acts as a nuclear transcription factor that positively regulates the expression of heat shock genes. Binds to heat shock promoter elements (HSE). {ECO:0000269PubMed:20162441}.
Subcellular Localization Nucleus {ECO:0000269PubMed:20162441}.
Disease Associations
Tissue Specificity Expressed strongly in testis and brain and weakly in prostate, spleen, pancreas and uterus. {ECO:0000269PubMed:20162441}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006366 transcription from RNA polymerase II promoter
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A1A519
PhosphoSite PhosphoSite-A1A519
TrEMBL
UniProt Splice Variant
Entrez Gene 340069
UniGene Hs.713304
RefSeq
HUGO HGNC:27963
OMIM
CCDS
HPRD 14174
IMGT
EMBL AC010409 AF427126 AY692447 BC040622 BC128243
GenPept AAH40622 AAI28244 AAP97296 AAU04855

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca