InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PSD2

Summary

InnateDB Protein

IDBP-48011.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PSD2

Protein Name

pleckstrin and Sec7 domain containing 2

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000274710

InnateDB Gene

IDBG-48009 (PSD2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005086	ARF guanyl-nucleotide exchange factor activity
GO:0005543	phospholipid binding

Biological Process

GO:0030182	neuron differentiation
GO:0032012	regulation of ARF protein signal transduction
GO:0043547	positive regulation of GTPase activity

Cellular Component

GO:0016021	integral component of membrane
GO:0030054	cell junction
GO:0030425	dendrite
GO:0043025	neuronal cell body

Protein Structure and Domains

PDB ID

InterPro

IPR000904 Sec7 domain
IPR001605 Pleckstrin homology domain, spectrin-type
IPR001849 Pleckstrin homology domain

PFAM

PF01369
PF00169

PRINTS

PR00683

PIRSF

SMART

SM00222
SM00233

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9BQI7

PhosphoSite

PhosphoSite-Q9BQI7

TrEMBL

UniProt Splice Variant

Entrez Gene

84249

UniGene

Hs.21963

RefSeq

NP_115665

HUGO

HGNC:19092

OMIM

CCDS

CCDS4216

HPRD

15190

IMGT

EMBL

AC008667 AL136559 AL834268 BC038233 CH471062

GenPept

AAH38233 CAB66494 CAD38943 EAW62088 EAW62089