Homo sapiens Protein: LRRC55 | |||||
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Summary | |||||
InnateDB Protein | IDBP-480390.3 | ||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
Gene Symbol | LRRC55 | ||||
Protein Name | leucine rich repeat containing 55 | ||||
Synonyms | |||||
Species | Homo sapiens | ||||
Ensembl Protein | ENSP00000419542 | ||||
InnateDB Gene | IDBG-46241 (LRRC55) | ||||
Protein Structure | |||||
UniProt Annotation | |||||
Function | Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Modulates gating properties by producing a marked shift in the BK channel's voltage dependence of activation in the hyperpolarizing direction, and in the absence of calcium. {ECO:0000269PubMed:22547800}. | ||||
Subcellular Localization | Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. | ||||
Disease Associations | |||||
Tissue Specificity | Mainly expressed in brain. {ECO:0000269PubMed:22547800}. | ||||
Comments | |||||
Interactions | |||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||
PDB ID | |||||
InterPro |
IPR000372
Leucine-rich repeat-containing N-terminal IPR000483 Cysteine-rich flanking region, C-terminal IPR001611 Leucine-rich repeat IPR003591 Leucine-rich repeat, typical subtype |
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PFAM |
PF01462
PF01463 PF00560 PF13504 PF13855 |
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PRINTS | |||||
PIRSF | |||||
SMART |
SM00013
SM00082 SM00369 |
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TIGRFAMs | |||||
Post-translational Modifications | |||||
Modification | |||||
Cross-References | |||||
SwissProt | Q6ZSA7 | ||||
PhosphoSite | PhosphoSite- | ||||
TrEMBL | |||||
UniProt Splice Variant | |||||
Entrez Gene | 219527 | ||||
UniGene | Hs.199853 | ||||
RefSeq | NP_001005210 | ||||
HUGO | HGNC:32324 | ||||
OMIM | 615213 | ||||
CCDS | CCDS31539 | ||||
HPRD | 16990 | ||||
IMGT | |||||
EMBL | AK127591 BC136737 BC136739 BC150572 | ||||
GenPept | AAI36738 AAI36740 AAI50573 BAC87047 | ||||