InnateDB Protein
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IDBP-480408.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CSF1R
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Protein Name
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colony stimulating factor 1 receptor
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Synonyms
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C-FMS; CD115; CSF-1R; CSFR; FIM2; FMS; HDLS; M-CSF-R;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000427545
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InnateDB Gene
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IDBG-53268 (CSF1R)
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Protein Structure
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Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 44 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Experimentally validated |
Total |
44
[view]
|
Protein-Protein |
35
[view]
|
Protein-DNA |
9
[view]
|
Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
19 [view]
|
|
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Molecular Function |
Accession |
GO Term |
GO:0004672
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protein kinase activity
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GO:0004714
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transmembrane receptor protein tyrosine kinase activity
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GO:0005524
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ATP binding
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GO:0016772
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transferase activity, transferring phosphorus-containing groups
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|
Biological Process |
GO:0006468
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protein phosphorylation
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GO:0007169
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transmembrane receptor protein tyrosine kinase signaling pathway
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GO:0018108
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peptidyl-tyrosine phosphorylation
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Cellular Component |
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PDB ID |
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InterPro |
IPR001245
Serine-threonine/tyrosine-protein kinase catalytic domain
IPR011009
Protein kinase-like domain
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PFAM |
PF07714
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PRINTS |
PR00109
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
|
PhosphoSite |
PhosphoSite-
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TrEMBL |
H0YAL5
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UniProt Splice Variant |
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Entrez Gene |
1436
|
UniGene |
Hs.586219
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RefSeq |
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HUGO |
HGNC:2433
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OMIM |
164770
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CCDS |
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HPRD |
01269
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IMGT |
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EMBL |
AC011382
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GenPept |
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