Version 5.4
Homo sapiens Protein: COX7C
Summary
InnateDB Protein IDBP-480544.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COX7C
Protein Name cytochrome c oxidase subunit VIIc
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000425759
InnateDB Gene IDBG-32682 (COX7C)
Protein Structure
UniProt Annotation
Function This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Subcellular Localization Mitochondrion inner membrane {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 2 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004129 cytochrome-c oxidase activity
Biological Process
GO:0006091 generation of precursor metabolites and energy
GO:0022904 respiratory electron transport chain
GO:0044237 cellular metabolic process
GO:0044281 small molecule metabolic process
GO:1902600 hydrogen ion transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR004202 Cytochrome c oxidase subunit VIIc
PFAM PF02935
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P15954
PhosphoSite PhosphoSite-P15954
TrEMBL A0A024RAP6
UniProt Splice Variant
Entrez Gene 1350
UniGene
RefSeq
HUGO HGNC:2292
OMIM 603774
CCDS CCDS4063
HPRD 04800
IMGT
EMBL AF067638 AF067639 BC001005 BC007498 BT007098 CH471084 X16560
GenPept AAC73062 AAH01005 AAH07498 AAP35762 CAA34559 EAW95922 EAW95924

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca