Version 5.4
Homo sapiens Protein: GIMAP2
Summary
InnateDB Protein IDBP-48066.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GIMAP2
Protein Name GTPase, IMAP family member 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000223293
InnateDB Gene IDBG-48064 (GIMAP2)
Protein Structure
UniProt Annotation
Function The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself. {ECO:0000269PubMed:23454188}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cytoplasm. Lipid droplet. Note=Detected on the surface of cytoplasmic lipid droplets.
Disease Associations
Tissue Specificity Detected in T-cells. {ECO:0000269PubMed:23454188}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005525 GTP binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0005811 lipid particle
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR006703 AIG1
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF04548
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UG22
PhosphoSite PhosphoSite-Q9UG22
TrEMBL
UniProt Splice Variant
Entrez Gene 26157
UniGene Hs.717720
RefSeq NP_056475
HUGO HGNC:21789
OMIM 608085
CCDS CCDS5905
HPRD 16279
IMGT
EMBL AL110151 BC013934 BC032345
GenPept AAH13934 AAH32345 CAB53662

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca