Version 5.4
Homo sapiens Protein: KCNQ3
Summary
InnateDB Protein IDBP-481020.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNQ3
Protein Name potassium voltage-gated channel, KQT-like subfamily, member 3
Synonyms BFNC2; EBN2; KV7.3;
Species Homo sapiens
Ensembl Protein ENSP00000429799
InnateDB Gene IDBG-35895 (KCNQ3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005249 voltage-gated potassium channel activity
GO:0005251 delayed rectifier potassium channel activity
GO:0005267 potassium channel activity
Biological Process
GO:0006811 ion transport
GO:0006813 potassium ion transport
GO:0007268 synaptic transmission
GO:0007411 axon guidance
GO:0034765 regulation of ion transmembrane transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0008076 voltage-gated potassium channel complex
GO:0016020 membrane
GO:0033268 node of Ranvier
GO:0043194 axon initial segment
Protein Structure and Domains
PDB ID
InterPro IPR003091 Potassium channel
IPR003937 Potassium channel, voltage dependent, KCNQ
IPR003948 Potassium channel, voltage dependent, KCNQ3
IPR005821 Ion transport domain
IPR013099 Two pore domain potassium channel domain
IPR013821 Potassium channel, voltage dependent, KCNQ, C-terminal
IPR020969 Ankyrin-G binding site
PFAM PF00520
PF07885
PF03520
PF11956
PRINTS PR00169
PR01459
PR01462
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O43525
PhosphoSite PhosphoSite-O43525
TrEMBL
UniProt Splice Variant
Entrez Gene 3786
UniGene Hs.374023
RefSeq NP_001191753
HUGO HGNC:6297
OMIM 602232
CCDS CCDS56554
HPRD 09077
IMGT
EMBL AC018540 AC123776 AC131042 AC136373 AF033347 AF071478 AF071479 AF071480 AF071481 AF071482 AF071483 AF071484 AF071485 AF071486 AF071487 AF071488 AF071489 AF071490 AF071491 AK296293 BC128576
GenPept AAB97314 AAC96101 AAI28577 BAG58996

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca