InnateDB Protein
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IDBP-481738.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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EIF1
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Protein Name
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eukaryotic translation initiation factor 1
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Synonyms
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A121; EIF-1; EIF1A; ISO1; SUI1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000419449
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InnateDB Gene
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IDBG-49651 (EIF1)
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Protein Structure
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Function |
Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
13
[view]
|
Protein-Protein |
12
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0003743
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translation initiation factor activity
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GO:0008135
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translation factor activity, nucleic acid binding
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GO:0044822
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poly(A) RNA binding
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001950
Translation initiation factor SUI1
IPR005874
Eukaryotic translation initiation factor SUI1
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PFAM |
PF01253
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PRINTS |
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PIRSF |
PIRSF004499
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P41567
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PhosphoSite |
PhosphoSite-P41567
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TrEMBL |
Q6IAV3
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UniProt Splice Variant |
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Entrez Gene |
102723417
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UniGene |
Hs.740876
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RefSeq |
NP_005792
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HUGO |
HGNC:3249
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OMIM |
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CCDS |
CCDS11403
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HPRD |
15449
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IMGT |
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EMBL |
AF083441
AF100737
AJ012375
AK311862
BC005118
BC008710
BT006645
CH471152
CR457051
L26247
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GenPept |
AAA60602
AAD19900
AAD52028
AAH05118
AAH08710
AAP35291
BAG34803
CAD66615
CAG33332
EAW60754
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