Version 5.4
Homo sapiens Protein: NFXL1
Summary
InnateDB Protein IDBP-481769.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NFXL1
Protein Name nuclear transcription factor, X-box binding-like 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000422037
InnateDB Gene IDBG-17008 (NFXL1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000967 Zinc finger, NF-X1-type
IPR001841 Zinc finger, RING-type
PFAM PF01422
PF13639
PF14634
PRINTS
PIRSF
SMART SM00438
SM00184
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6ZNB6
PhosphoSite PhosphoSite-Q6ZNB6
TrEMBL
UniProt Splice Variant
Entrez Gene 152518
UniGene Hs.646325
RefSeq NP_001265553
HUGO HGNC:18726
OMIM
CCDS CCDS3478
HPRD 11025
IMGT
EMBL AB181916 AC107068 AK131285 AK302440 BC018019 BC051193
GenPept AAH18019 AAH51193 AAY40918 BAD18459 BAG16261 BAH13710

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca