InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HARS2

Summary

InnateDB Protein

IDBP-482204.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HARS2

Protein Name

histidyl-tRNA synthetase 2, mitochondrial (putative)

Synonyms

HARSL; HARSR; HO3; PRLTS2;

Species

Homo sapiens

Ensembl Protein

ENSP00000423616

InnateDB Gene

IDBG-49399 (HARS2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004812	aminoacyl-tRNA ligase activity
GO:0004821	histidine-tRNA ligase activity
GO:0005524	ATP binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006412	translation
GO:0006418	tRNA aminoacylation for protein translation
GO:0006427	histidyl-tRNA aminoacylation
GO:0010467	gene expression

Cellular Component

GO:0005737	cytoplasm
GO:0005759	mitochondrial matrix

Protein Structure and Domains

PDB ID

InterPro

IPR002314 Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain
IPR004154 Anticodon-binding
IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit
IPR006195 Aminoacyl-tRNA synthetase, class II
IPR015807 Histidine-tRNA ligase

PFAM

PF00587
PF03129

PRINTS

PIRSF

PIRSF001549

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P49590