Version 5.4
Homo sapiens Protein: KLC4
Summary
InnateDB Protein IDBP-482273.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KLC4
Protein Name kinesin light chain 4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000418759
InnateDB Gene IDBG-87735 (KLC4)
Protein Structure
UniProt Annotation
Function Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 22 [view]
Protein-Protein 21 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003777 microtubule motor activity
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005871 kinesin complex
GO:0005874 microtubule
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NSK0
PhosphoSite PhosphoSite-Q9NSK0
TrEMBL C9JXT5
UniProt Splice Variant
Entrez Gene 89953
UniGene Hs.655123
RefSeq
HUGO HGNC:21624
OMIM
CCDS
HPRD 13932
IMGT
EMBL AK055293 AK056393 AK094102 AK127018 AK127894 AL136304 AL162078 AL355385 BC012357 BC080637 BC103727 BX640717 CH471081
GenPept AAH12357 AAH80637 AAI03728 BAC86788 BAC87179 BAG51496 BAG51695 BAG52815 CAB82411 CAE45836 CAI13781 EAX04149

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca