Version 5.4
Homo sapiens Protein: PIK3CG
Summary
InnateDB Protein IDBP-482336.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PIK3CG
Protein Name phosphoinositide-3-kinase, catalytic, gamma polypeptide
Synonyms p110gamma; p120-PI3K; PI3CG; PI3K; PI3Kgamma; PIK3;
Species Homo sapiens
Ensembl Protein ENSP00000417623
InnateDB Gene IDBG-35338 (PIK3CG)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 44 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 44 [view]
Protein-Protein 43 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0048015 phosphatidylinositol-mediated signaling
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain
IPR011009 Protein kinase-like domain
PFAM PF00454
PRINTS
PIRSF
SMART SM00146
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q24M88
UniProt Splice Variant
Entrez Gene 5294
UniGene Hs.684154
RefSeq
HUGO HGNC:8978
OMIM 601232
CCDS
HPRD 03135
IMGT
EMBL AC005018 AY496423
GenPept AAS75801

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca