Version 5.4
Homo sapiens Protein: CHRFAM7A
Summary
InnateDB Protein IDBP-4824.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CHRFAM7A
Protein Name CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000299847
InnateDB Gene IDBG-4822 (CHRFAM7A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in hippocampus. {ECO:0000269PubMed:9782083}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005230 extracellular ligand-gated ion channel activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0034220 ion transmembrane transport
GO:0034766 negative regulation of ion transmembrane transport
GO:1903049 negative regulation of acetylcholine-gated cation channel activity
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
IPR006201 Neurotransmitter-gated ion-channel
IPR006202 Neurotransmitter-gated ion-channel ligand-binding
PFAM PF02932
PF02931
PRINTS PR00252
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q494W8
PhosphoSite PhosphoSite-
TrEMBL Q693P7
UniProt Splice Variant
Entrez Gene 89832
UniGene Hs.537548
RefSeq NP_647536
HUGO HGNC:15781
OMIM 609756
CCDS CCDS32184
HPRD 18704
IMGT
EMBL AC010799 AC019322 AF029838 AH013945 AK292984 BC101346 BC101347 BC101348
GenPept AAI01347 AAI01348 AAI01349 AAT81394 BAF85673

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca