InnateDB Protein
|
IDBP-482436.2
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
CLDN23
|
Protein Name
|
claudin 23
|
Synonyms
|
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000428780
|
InnateDB Gene
|
IDBG-403101 (CLDN23)
|
Protein Structure
|
|
Function |
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. {ECO:0000250}.
|
Subcellular Localization |
Cell junction, tight junction {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
Disease Associations |
|
Tissue Specificity |
Expressed in germinal center B-cells, placenta, stomach as well as in colon tumor. {ECO:0000269PubMed:12736707}.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR004031
PMP-22/EMP/MP20/Claudin superfamily
IPR006187
Claudin
|
PFAM |
PF00822
PF13903
|
PRINTS |
PR01077
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q96B33
|
PhosphoSite |
PhosphoSite-Q96B33
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
137075
|
UniGene |
Hs.183617
|
RefSeq |
NP_919260
|
HUGO |
HGNC:17591
|
OMIM |
609203
|
CCDS |
CCDS55195
|
HPRD |
13069
|
IMGT |
|
EMBL |
BC125148
BC125149
|
GenPept |
AAI25149
AAI25150
|
|
|