Version 5.4
Homo sapiens Protein: SIPA1L3
Summary
InnateDB Protein IDBP-48251.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SIPA1L3
Protein Name signal-induced proliferation-associated 1 like 3
Synonyms SPAL3;
Species Homo sapiens
Ensembl Protein ENSP00000222345
InnateDB Gene IDBG-48249 (SIPA1L3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0005515 protein binding
Biological Process
GO:0002244 hematopoietic progenitor cell differentiation
GO:0043547 positive regulation of GTPase activity
GO:0051056 regulation of small GTPase mediated signal transduction
Cellular Component
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID
InterPro IPR000331 Rap GTPase activating protein domain
IPR001478 PDZ domain
IPR021818 Protein of unknown function DUF3401
PFAM PF02145
PF00595
PF13180
PF11881
PRINTS
PIRSF
SMART SM00228
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O60292
PhosphoSite PhosphoSite-O60292
TrEMBL Q8IUV1
UniProt Splice Variant
Entrez Gene 23094
UniGene Hs.655502
RefSeq NP_055888
HUGO HGNC:23801
OMIM
CCDS CCDS33007
HPRD 18755
IMGT
EMBL AB011117 AY168880 BC036863
GenPept AAH36863 AAO12531 BAA25471

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca