Version 5.4
Homo sapiens Protein: TCOF1
Summary
InnateDB Protein IDBP-482619.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TCOF1
Protein Name Treacher Collins-Franceschetti syndrome 1
Synonyms MFD1; TCS; TCS1; treacle;
Species Homo sapiens
Ensembl Protein ENSP00000427484
InnateDB Gene IDBG-53504 (TCOF1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 47 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 47 [view]
Protein-Protein 46 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR003993 Treacher Collins syndrome, treacle
IPR006594 LisH dimerisation motif
IPR017859 Treacle-like, Treacher Collins Syndrome
PFAM PF03546
PRINTS PR01503
PIRSF
SMART SM00667
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9UFD4
UniProt Splice Variant
Entrez Gene 6949
UniGene Hs.519672
RefSeq XP_005268563
HUGO HGNC:11654
OMIM 606847
CCDS
HPRD 06026
IMGT
EMBL AC011372 AL133039
GenPept CAB61367

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca