Version 5.4
Homo sapiens Protein: TFAP2A
Summary
InnateDB Protein IDBP-482799.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TFAP2A
Protein Name transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
Synonyms AP-2; AP-2alpha; AP2TF; BOFS; TFAP2;
Species Homo sapiens
Ensembl Protein ENSP00000417495
InnateDB Gene IDBG-60624 (TFAP2A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 55 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 55 [view]
Protein-Protein 45 [view]
Protein-DNA 9 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
Biological Process
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005813 centrosome
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID
InterPro IPR008121 Transcription factor AP-2 alpha, N-terminal
IPR013854 Transcription factor AP-2, C-terminal
PFAM PF03299
PRINTS PR01749
PR01748
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C1K3N0
UniProt Splice Variant
Entrez Gene 7020
UniGene Hs.657734
RefSeq
HUGO HGNC:11742
OMIM 107580
CCDS
HPRD 00128
IMGT
EMBL AL138885 FJ794945
GenPept ACN93799

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca