InnateDB Protein
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IDBP-482863.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ZNF260
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Protein Name
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zinc finger protein 260
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000429803
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InnateDB Gene
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IDBG-409408 (ZNF260)
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Protein Structure
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Function |
Transcription factor that acts as a cardiac regulator and an effector of alpha1-adrenergic signaling. Binds to PE response elements (PERE) present in the promoter of genes such as ANF/NPPA and acts as a direct transcriptional activator of NPPA. Also acts as a cofactor with GATA4, a key cardiac regulator (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000269PubMed:16166646}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR007087
Zinc finger, C2H2
IPR015880
Zinc finger, C2H2-like
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PFAM |
PF00096
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PRINTS |
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PIRSF |
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SMART |
SM00355
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TIGRFAMs |
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Modification |
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SwissProt |
Q3ZCT1
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PhosphoSite |
PhosphoSite-Q3ZCT1
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
339324
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UniGene |
Hs.18103
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RefSeq |
NP_001159510
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HUGO |
HGNC:13499
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OMIM |
613749
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CCDS |
CCDS33003
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HPRD |
18505
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IMGT |
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EMBL |
AC092295
BC042676
BC119003
BC122549
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GenPept |
AAH42676
AAI19004
AAI22550
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