Version 5.4
Homo sapiens Protein: HARS
Summary
InnateDB Protein IDBP-483376.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HARS
Protein Name histidyl-tRNA synthetase
Synonyms HRS; USH3B;
Species Homo sapiens
Ensembl Protein ENSP00000425889
InnateDB Gene IDBG-49355 (HARS)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 34 experimentally validated interaction(s) in this database.
Experimentally validated
Total 34 [view]
Protein-Protein 32 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004812 aminoacyl-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000738 WHEP-TRS
IPR009068 S15/NS1, RNA-binding
PFAM PF00458
PRINTS
PIRSF
SMART SM00991
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E7ETE2
UniProt Splice Variant
Entrez Gene 3035
UniGene Hs.595156
RefSeq
HUGO HGNC:4816
OMIM 142810
CCDS
HPRD 00827
IMGT
EMBL AC116353 AK293531
GenPept BAG57013

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca