InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SLC15A2

Summary

InnateDB Protein

IDBP-483382.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC15A2

Protein Name

solute carrier family 15 (H+/peptide transporter), member 2

Synonyms

PEPT2;

Species

Homo sapiens

Ensembl Protein

ENSP00000417085

InnateDB Gene

IDBG-52251 (SLC15A2)

Protein Structure

UniProt Annotation

Function

Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides.

Subcellular Localization

Membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0005515	protein binding
GO:0015198	oligopeptide transporter activity
GO:0015333	peptide:hydrogen symporter activity
GO:0015334	high affinity oligopeptide transporter activity
GO:0042895	antibiotic transporter activity
GO:0042936	dipeptide transporter activity

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0006857	oligopeptide transport
GO:0015031	protein transport
GO:0015893	drug transport
GO:0015992	proton transport
GO:0042891	antibiotic transport
GO:0042938	dipeptide transport
GO:0055085	transmembrane transport

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000109 Proton-dependent oligopeptide transporter family
IPR004768 Oligopeptide transporter
IPR016196 Major facilitator superfamily domain, general substrate transporter
IPR029028 Alpha/beta knot methyltransferases

PFAM

PF00854

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q16348

PhosphoSite