Version 5.4
Homo sapiens Protein: TPD52
Summary
InnateDB Protein IDBP-483788.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TPD52
Protein Name tumor protein D52
Synonyms D52; hD52; N8L; PC-1; PrLZ;
Species Homo sapiens
Ensembl Protein ENSP00000429915
InnateDB Gene IDBG-26337 (TPD52)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity Isoform 2 is expressed in colon, breast, prostate, pancreas and kidney tumor cell lines. Isoform 2 is expressed at high levels in kidney, prostate, brain, small intestine and pancreas, at moderate levels in placenta and colon, at low levels in lung, liver and heart, and at very low levels in spleen, thymus, peripheral mononuclear blood cells, testis and ovary. {ECO:0000269PubMed:8632896}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
Experimentally validated
Total 26 [view]
Protein-Protein 26 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
GO:0046982 protein heterodimerization activity
Biological Process
GO:0009653 anatomical structure morphogenesis
GO:0030183 B cell differentiation
GO:0046903 secretion
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR007327 Tumour protein D52
PFAM PF04201
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P55327
PhosphoSite PhosphoSite-P55327
TrEMBL E5RK35
UniProt Splice Variant
Entrez Gene 7163
UniGene Hs.692896
RefSeq NP_001020424
HUGO HGNC:12005
OMIM 604068
CCDS CCDS47879
HPRD 04963
IMGT
EMBL AC009686 AC018952 AC036214 AC104212 AF202897 AK223631 AK295468 AK296615 AK313135 BC018117 BT019444 BX640835 CH471068 CR542034 CR542064 GQ499324 GQ499325 GQ499326 GQ499327 GQ499328 S82081 U18914
GenPept AAB36475 AAC50183 AAH18117 AAO22156 AAV38251 ACY08776 ACY08777 ACY08778 ACY08779 ACY08780 BAD97351 BAG35954 BAH12078 BAH12400 CAE45908 CAG46831 CAG46861 EAW87074

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca