Version 5.4
Homo sapiens Protein: ERMP1
Summary
InnateDB Protein IDBP-483965.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ERMP1
Protein Name endoplasmic reticulum metallopeptidase 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000417160
InnateDB Gene IDBG-47838 (ERMP1)
Protein Structure
UniProt Annotation
Function Within the ovary, required for the organization of somatic cells and oocytes into discrete follicular structures. {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008237 metallopeptidase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0008152 metabolic process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR002933 Peptidase M20
IPR007484 Peptidase M28
PFAM PF01546
PF04389
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7Z2K6
PhosphoSite PhosphoSite-Q7Z2K6
TrEMBL D3DRI3
UniProt Splice Variant
Entrez Gene 79956
UniGene Hs.717552
RefSeq
HUGO HGNC:23703
OMIM 611156
CCDS CCDS34983
HPRD 17227
IMGT
EMBL AB058718 AK026962 AK127218 BC031630 BC136771 BC136773 CH471071
GenPept AAH31630 AAI36772 AAI36774 BAB15604 BAB47444 BAG54455 EAW58757 EAW58758

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca