Version 5.4
Homo sapiens Protein: PAQR3
Summary
InnateDB Protein IDBP-484058.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PAQR3
Protein Name progestin and adipoQ receptor family member III
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000422357
InnateDB Gene IDBG-26290 (PAQR3)
Protein Structure
UniProt Annotation
Function Functions as a spatial regulator of RAF1 kinase by sequestrating it to the Golgi. {ECO:0000269PubMed:18547165}.
Subcellular Localization Golgi apparatus membrane {ECO:0000269PubMed:18547165}; Multi-pass membrane protein {ECO:0000269PubMed:18547165}.
Disease Associations
Tissue Specificity Widely expressed in a range of tissues. {ECO:0000269PubMed:16044242}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
Biological Process
GO:0001933 negative regulation of protein phosphorylation
GO:0010977 negative regulation of neuron projection development
GO:0033137 negative regulation of peptidyl-serine phosphorylation
GO:0034067 protein localization to Golgi apparatus
GO:0043407 negative regulation of MAP kinase activity
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6TCH7
PhosphoSite PhosphoSite-Q6TCH7
TrEMBL
UniProt Splice Variant
Entrez Gene 152559
UniGene Hs.732586
RefSeq
HUGO HGNC:30130
OMIM 614577
CCDS
HPRD 17819
IMGT
EMBL AK055774 AK291232 AY424281 BC029604 BC031256 BC047510
GenPept AAH31256 AAH47510 AAR08369 BAF83921 BAG51571

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca