Version 5.4
Homo sapiens Protein: SERPINB11
Summary
InnateDB Protein IDBP-484088.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SERPINB11
Protein Name serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000421854
InnateDB Gene IDBG-4528 (SERPINB11)
Protein Structure
UniProt Annotation
Function Has no serine protease inhibitory activity, probably due to mutations in the scaffold impairing conformational change. {ECO:0000269PubMed:17562709}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity Detected in a restricted number of tissues, including lung, placenta, prostate, and tonsil. {ECO:0000269PubMed:17562709}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
Biological Process
GO:0010951 negative regulation of endopeptidase activity
GO:0030162 regulation of proteolysis
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR023796 Serpin domain
PFAM PF00079
PRINTS
PIRSF
SMART SM00093
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96P15
PhosphoSite PhosphoSite-Q96P15
TrEMBL F5GYW9
UniProt Splice Variant
Entrez Gene 89778
UniGene Hs.350958
RefSeq
HUGO HGNC:14221
OMIM 615682
CCDS
HPRD 11547
IMGT
EMBL AC069356 AF419953 AF419954 AF419955 AK292775 AY792323 AY792324 AY792325 AY792326 BC069596
GenPept AAH69596 AAL16056 AAL16057 AAL16058 AAV73920 AAV73921 AAV73922 AAV73923 BAF85464

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca