Version 5.4
Homo sapiens Protein: ZBTB20
Summary
InnateDB Protein IDBP-484158.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZBTB20
Protein Name zinc finger and BTB domain containing 20
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000419153
InnateDB Gene IDBG-50911 (ZBTB20)
Protein Structure
UniProt Annotation
Function May be a transcription factor that may be involved in hematopoiesis, oncogenesis, and immune responses. {ECO:0000269PubMed:11352661}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in spleen, lymph node, thymus, peripheral blood leukocytes, and fetal liver. {ECO:0000269PubMed:11352661}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 4 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR000210 BTB/POZ-like
IPR007087 Zinc finger, C2H2
IPR011333 BTB/POZ fold
IPR013069 BTB/POZ
IPR015880 Zinc finger, C2H2-like
PFAM PF00096
PF00651
PRINTS
PIRSF
SMART SM00225
SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9HC78
PhosphoSite PhosphoSite-Q9HC78
TrEMBL C9JCX0
UniProt Splice Variant
Entrez Gene 26137
UniGene
RefSeq NP_001157814
HUGO HGNC:13503
OMIM 606025
CCDS CCDS54626
HPRD 05822
IMGT
EMBL AC055739 AC069063 AC069506 AC078986 AC083886 AC092915 AC131152 AC138977 AF139460 AL050276 BC029041 BX647778 CH471052
GenPept AAG28340 AAH29041 CAB43377 CAH56190 EAW79598

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca