Version 5.4
Homo sapiens Protein: SPINK2
Summary
InnateDB Protein IDBP-484321.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPINK2
Protein Name serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
Synonyms HUSI-II;
Species Homo sapiens
Ensembl Protein ENSP00000425961
InnateDB Gene IDBG-20299 (SPINK2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0002176 male germ cell proliferation
GO:0007283 spermatogenesis
GO:0007286 spermatid development
GO:0008584 male gonad development
GO:0009566 fertilization
GO:0072520 seminiferous tubule development
GO:1900004 negative regulation of serine-type endopeptidase activity
Cellular Component
GO:0001669 acrosomal vesicle
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR002350 Kazal domain
PFAM PF00050
PF07648
PRINTS
PIRSF
SMART SM00280
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D6RI10
UniProt Splice Variant
Entrez Gene 6691
UniGene Hs.98243
RefSeq NP_001258647
HUGO HGNC:11245
OMIM 605753
CCDS CCDS63971
HPRD 10422
IMGT
EMBL AC022483
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca