Version 5.4
Homo sapiens Protein: NEDD9
Summary
InnateDB Protein IDBP-484615.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NEDD9
Protein Name neural precursor cell expressed, developmentally down-regulated 9
Synonyms CAS-L; CAS2; CASL; CASS2; HEF1;
Species Homo sapiens
Ensembl Protein ENSP00000422871
InnateDB Gene IDBG-61538 (NEDD9)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 54 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 54 [view]
Protein-Protein 54 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007010 cytoskeleton organization
GO:0007067 mitotic nuclear division
GO:0007155 cell adhesion
GO:0007165 signal transduction
GO:0007229 integrin-mediated signaling pathway
GO:0040008 regulation of growth
GO:0051017 actin filament bundle assembly
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005819 spindle
GO:0005925 focal adhesion
GO:0005938 cell cortex
GO:0030027 lamellipodium
Protein Structure and Domains
PDB ID
InterPro IPR001452 SH3 domain
IPR011511 Variant SH3 domain
IPR014928 Serine rich protein interaction
IPR021901 CAS family, DUF3513
PFAM PF00018
PF14604
PF07653
PF08824
PF12026
PRINTS PR00452
PIRSF
SMART SM00326
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q14511
PhosphoSite PhosphoSite-Q14511
TrEMBL D6RGD7
UniProt Splice Variant
Entrez Gene 4739
UniGene Hs.737232
RefSeq NP_001135865
HUGO HGNC:7733
OMIM 602265
CCDS CCDS47373
HPRD 11888
IMGT
EMBL AK292682 AL022098 AL136139 AL139807 AL512382 BC020686 BC040207 CH471087 L43821 U64317
GenPept AAA98770 AAB53696 AAH20686 AAH40207 BAF85371 CAI21579 CAI21580 CAI22676 CAI22677 EAW55299 EAW55300 EAW55301

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca