InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: KIAA1191

Summary

InnateDB Protein

IDBP-484656.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KIAA1191

Protein Name

KIAA1191

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000421061

InnateDB Gene

IDBG-58712 (KIAA1191)

Protein Structure

UniProt Annotation

Function

Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth.

Subcellular Localization

Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Down-regulated in the occipital lobe of an early stage Alzheimer disease patients. {ECO:0000269PubMed:17032350}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0016491	oxidoreductase activity

Biological Process

GO:0008150	biological_process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005575	cellular_component
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q96A73

PhosphoSite

PhosphoSite-Q96A73

TrEMBL

D6RF63

UniProt Splice Variant

Entrez Gene

57179

UniGene

Hs.743257

RefSeq

NP_001073153

HUGO

HGNC:29209

OMIM

CCDS

CCDS4399

HPRD

13839

IMGT

EMBL

AB033017 AC138956 AK024675 AK315428 AL390217 BC006316 BC010448 BC012848 BC017097 BX648859 CH471195 CR457331 DQ073392

GenPept

AAH06316 AAH10448 AAH12848 AAH17097 AAY82896 BAA86505 BAB14957 BAG37816 CAB99231 CAG33612 CAH56134 EAW85087 EAW85088 EAW85089 EAW85091 EAW85093