Version 5.4
Homo sapiens Protein: POLB
Summary
InnateDB Protein IDBP-484691.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POLB
Protein Name polymerase (DNA directed), beta
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000429436
InnateDB Gene IDBG-20094 (POLB)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 24 [view]
Protein-Protein 22 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0034061 DNA polymerase activity
Biological Process
GO:0006261 DNA-dependent DNA replication
GO:0006281 DNA repair
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR002008 DNA polymerase family X, beta-like
IPR002054 DNA-directed DNA polymerase X
IPR003583 Helix-hairpin-helix DNA-binding motif, class 1
IPR010996 DNA polymerase beta-like, N-terminal domain
IPR018944 DNA polymerase lambda, fingers domain
PFAM PF10391
PRINTS PR00870
PIRSF
SMART SM00483
SM00278
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E5RIJ0
UniProt Splice Variant
Entrez Gene 5423
UniGene Hs.661106
RefSeq
HUGO HGNC:9174
OMIM 174760
CCDS
HPRD 07517
IMGT
EMBL AC083973 AC107885
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca