Version 5.4
Homo sapiens Protein: PARP8
Summary
InnateDB Protein IDBP-484964.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PARP8
Protein Name poly (ADP-ribose) polymerase family, member 8
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000422217
InnateDB Gene IDBG-20083 (PARP8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003950 NAD+ ADP-ribosyltransferase activity
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005622 intracellular
Protein Structure and Domains
PDB ID
InterPro IPR012317 Poly(ADP-ribose) polymerase, catalytic domain
PFAM PF00644
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N3A8
PhosphoSite PhosphoSite-Q8N3A8
TrEMBL D6RGZ9
UniProt Splice Variant
Entrez Gene 79668
UniGene Hs.741804
RefSeq NP_001171526
HUGO HGNC:26124
OMIM
CCDS CCDS3954
HPRD 07960
IMGT
EMBL AC008919 AC022441 AC112187 AK024961 AL834477 BC075801 BC105789
GenPept AAH75801 AAI05790 BAB15044 CAD39136

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca